Janeway's Immunobiology

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Janeway's Immunobiology,

von: Kenneth M. Murphy, Paul Travers, Mark Walport

Janeway's Immunobiology
Bindung: Taschenbuch
Dewey-Dezimalklassifikation: 616.079
EAN: 9780815341239
Ausgabe: 7th Revised edition (REV).
ISBN: 0815341237
Label: Taylor & Francis
Hersteller: Taylor & Francis
Anzahl Seiten: 887
Erscheinungsdatum: Januar 02, 2008
Herausgeber: Taylor & Francis
Studio: Taylor & Francis

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Bewertung: - Janeway's Immunobiology
This book ist a wonderful tool for studying immunology and I recommend to use it. Unfortunately I have to point to one subject that is to critisize because it involves major human and pet diseases.

That is the lack of the pregnancy hormone progesterone as a topic of discussion. Besides cortisole progesterone is the mayor hormone for immunmodulation. It changes the cellular immunity to the Th2 type. During pregnancy that ist presumely important for the embryo to protect it from the immune surveillance of the mother.

In cancer and several diseases we find the same change of the cellular immunity. Similar to pregnancy natural killer cells are inactivated by progesterone dependent proteins like PIBF (Check JH 2007). PIBF means progesterene induced blocking factor and it blocks the natural killer cells which by this way are hindered to kill tumor cells.

Where does the progesterone come from?
For example in an old man suffering form carcinoma of the ... weiter

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